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| Acura
Pharmaceuticals, Inc.
Acura Pharmaceuticals, Inc. is a specialty pharmaceutical company engaged in
research, development and manufacture of innovative Aversion® (abuse deterrent)
Technology and related product candidates.
Aversion®
Technology
Aversion®
Technology is a
patented platform for developing pharmaceutical products containing
potentially abuseable drugs including oxycodone, hydrocodone, oxymorphone,
hydromorphone, morphine, codeine, tramadol, propoxyphene, and many other
opioid analgesics.
We believe this platform technology
is also applicable to non-opioid
products that are subject to abuse and which fall into two broad categories,
central nervous system ("CNS") depressants (including tranquilizers and
sedatives) and stimulants.
Aversion® Technology is applicable to orally administered
tablets and capsules. In addition to the active ingredient, Aversion® Technology
utilizes certain proprietary combinations of inactive excipients and active
ingredients intended to discourage the most common methods of pharmaceutical
product misues and abuse including;

(i) intravenous injection of dissolved tablets or
capsules,
(ii) nasal snorting of crushed tablets or capsules
(iii) intentional swallowing of excessive quantities of tablets or
capsules
. . .
More
ACUROX™ Tablets
ACUROX™
Tablets (oxycodone HCl and niacin),
is the Company’s lead product candidate with Aversion® (abuse deterrent)
Technology. . .
More
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Patents

In April 2007, the United States Patent and Trademark Office (the
“USPTO”) issued to the Company U.S. Patent No. 7,201,920 titled ”Methods and
Compositions for Deterring Abuse of Opioid Containing Dosage
Forms”. The 54 allowed patent claims encompass pharmaceutical
compositions intended to reduce or discourage the three most
common methods of prescription opioid analgesic product misuse
and abuse (the Company's "Aversion® Technology") including; (i)
intravenous injection of dissolved tablets or capsules; (ii)
snorting of crushed tablets or capsules and; (iii) intentionally
swallowing excess quantities of tablets or capsules. The opioid
analgesics in the issued patent claims include oxycodone, hydrocodone, hydromorphone, morphine, codeine, tramadol,
propoxyphene and many others.
In addition to issued
U.S. Patent No. 7,201,920, the Company has pending five U.S.
non-provisional patent applications, three WO/PCT patent
applications and multiple additional U.S. provisional and international
patent filings relating to compositions containing abuseable drugs.
At present, except for the rights conferred in the King
Agreement, the Company retains ownership of all intellectual
property and commercial rights to its Aversion® Technology and
related product candidates.
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